Gender differences in cortical glucose metabolism in Alzheimer's disease and normal aging
- Author(s): Siegel, BV
- Shihabuddin, L
- Buchsbaum, MS
- Starr, A
- Haier, RJ
- Valladares Neto, DC
- et al.
Published Web Locationhttps://doi.org/10.1176/jnp.8.2.211
Male Alzheimer's disease patients, studied with 18-fluoro-2-deoxyglucose positron emission tomography while performing a verbal memory test, showed a right-greater-than-left asymmetry of cortical metabolism that tended to be greater than that in healthy, age-matched control subjects. This asymmetry was absent in female patients, preliminarily suggesting a propensity for left hemispheric involvement in the Alzheimer's disease process in males.
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