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Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
Published Web Location
https://doi.org/10.1038/nature09161Abstract
A marker for cancer stem cellsA number of studies have reported the existence of cancer stem cells in human melanomas, each one capable of producing a tumour. Boiko et al. examined a broad spectrum of clinical samples taken from melanomas and report that the neural crest stem-cell marker CD271 is a marker for cancer stem cells, allowing the identification and prospective isolation of melanoma cancer stem cells.
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