- Main
Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery
- Coussens, Nathan P;
- Sittampalam, G Sitta;
- Guha, Rajarshi;
- Brimacombe, Kyle;
- Grossman, Abigail;
- Chung, Thomas DY;
- Weidner, Jeffrey R;
- Riss, Terry;
- Trask, O Joseph;
- Auld, Douglas;
- Dahlin, Jayme L;
- Devanaryan, Viswanath;
- Foley, Timothy L;
- McGee, James;
- Kahl, Steven D;
- Kales, Stephen C;
- Arkin, Michelle;
- Baell, Jonathan;
- Bejcek, Bruce;
- Gal‐Edd, Neely;
- Glicksman, Marcie;
- Haas, Joseph V;
- Iversen, Philip W;
- Hoeppner, Marilu;
- Lathrop, Stacy;
- Sayers, Eric;
- Liu, Hanguan;
- Trawick, Bart;
- McVey, Julie;
- Lemmon, Vance P;
- Li, Zhuyin;
- McManus, Owen;
- Minor, Lisa;
- Napper, Andrew;
- Wildey, Mary Jo;
- Pacifici, Robert;
- Chin, William W;
- Xia, Menghang;
- Xu, Xin;
- Lal‐Nag, Madhu;
- Hall, Matthew D;
- Michael, Sam;
- Inglese, James;
- Simeonov, Anton;
- Austin, Christopher P
- et al.
Published Web Location
https://doi.org/10.1111/cts.12570Abstract
The Assay Guidance Manual (AGM) is an eBook of best practices for the design, development, and implementation of robust assays for early drug discovery. Initiated by pharmaceutical company scientists, the manual provides guidance for designing a "testing funnel" of assays to identify genuine hits using high-throughput screening (HTS) and advancing them through preclinical development. Combined with a workshop/tutorial component, the overall goal of the AGM is to provide a valuable resource for training translational scientists.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.
Main Content
Enter the password to open this PDF file:
-
-
-
-
-
-
-
-
-
-
-
-
-
-