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Elevated pulmonary artery systolic pressures are associated with a lower risk of atrial fibrillation following lung transplantation
Published Web Location
https://doi.org/10.1016/j.jelectrocard.2012.07.014Abstract
Background
Atrial fibrillation (AF) is common after open-chest procedures, but the etiology remains poorly understood. Lung transplant procedures allow for the study of novel contributing factors.Methods
Records of lung transplant procedures performed at a single center between 2002 and 2009 were reviewed.Results
Of 174 patients, 27 (16%) had AF a median 6 days post-surgery. Post-operative AF patients less often had right ventricular hypertrophy (RVH) by either electrocardiogram (0 versus 14%, P=.042) or echocardiography (19% versus 47%, P=.006), and had lower pulmonary artery systolic pressures (PASP) (39 ± 12 versus 51 ± 22, P=.005). After multivariable adjustment, every 10-mm Hg increase in PASP was associated with a 31% reduction in the odds of post-operative AF (OR 0.69, 95% CI 0.49-0.98, P=.035). A higher pulmonary pressure was the only predictor independently associated with less post-operative AF.Conclusions
Higher PASP was associated with a lower risk of AF after lung transplantation.Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.