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Coactivation of thalamic and cortical pathways induces input timing–dependent plasticity in amygdala
- Cho, Jun-Hyeong;
- Bayazitov, Ildar T;
- Meloni, Edward G;
- Myers, Karyn M;
- Carlezon, William A;
- Zakharenko, Stanislav S;
- Bolshakov, Vadim Y
Published Web Location
https://doi.org/10.1038/nn.2993Abstract
The authors show that paired stimulation of thalamic and cortical auditory inputs to the lateral nucleus of the amygdala, with the interstimulus interval mimicking their activation in behaving animals during auditory fear conditioning, results in persistent potentiation of synaptic transmission in the cortico-amygdala pathway in rat brain slices.
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