Computational Engine for a Virtual Tissue Simulator
Abstract
We have developed a computational platform that simulates light transport in tissue in support of biomedical optics research. Although in its initial stage of development, this platform is being used to answer important questions regarding the detection of tissue changes, and the optimal design and positioning of optical probes to 'interrogate' the tissue best. We provide answers to such questions by applying perturbation and midway surface Monte Carlo techniques. Derivation of these methods makes rigorous use of the radiative transport equation which is essential if the methods are to provide accurate solutions for highly complex media such as biological tissue. © 2008 Springer-Verlag Berlin Heidelberg.
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