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Diagnostic assay to assist clinical decisions for unclassified severe combined immune deficiency
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https://doi.org/10.1182/bloodadvances.2020001736Abstract
3D organoid T-cell differentiation from a few hundred peripheral blood CD34+ cells was successfully achieved. 3D organoid T-cell differentiation could help physicians distinguish intrinsic from extrinsic defects underlying a clinical SCID phenotype.
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