Skip to main content
eScholarship
Open Access Publications from the University of California

Race and ancestry in biomedical research: exploring the challenges.

  • Author(s): Caulfield, Timothy
  • Fullerton, Stephanie M
  • Ali-Khan, Sarah E
  • Arbour, Laura
  • Burchard, Esteban G
  • Cooper, Richard S
  • Hardy, Billie-Jo
  • Harry, Simrat
  • Hyde-Lay, Robyn
  • Kahn, Jonathan
  • Kittles, Rick
  • Koenig, Barbara A
  • Lee, Sandra Sj
  • Malinowski, Michael
  • Ravitsky, Vardit
  • Sankar, Pamela
  • Scherer, Stephen W
  • Séguin, Béatrice
  • Shickle, Darren
  • Suarez-Kurtz, Guilherme
  • Daar, Abdallah S
  • et al.

Published Web Location

https://doi.org/10.1186/gm8
Abstract

The use of race in biomedical research has, for decades, been a source of social controversy. However, recent events, such as the adoption of racially targeted pharmaceuticals, have raised the profile of the race issue. In addition, we are entering an era in which genomic research is increasingly focused on the nature and extent of human genetic variation, often examined by population, which leads to heightened potential for misunderstandings or misuse of terms concerning genetic variation and race. Here, we draw together the perspectives of participants in a recent interdisciplinary workshop on ancestry and health in medicine in order to explore the use of race in research issue from the vantage point of a variety of disciplines. We review the nature of the race controversy in the context of biomedical research and highlight several challenges to policy action, including restrictions resulting from commercial or regulatory considerations, the difficulty in presenting precise terminology in the media, and drifting or ambiguous definitions of key terms.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
Current View