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Luffariellolide, an anti-inflammatory sesterterpene from the marine spongeLuffariella sp.

Abstract

Luffariellolide (2) is a sesterterpene from the Palauan sponge Luffariella sp. that has useful anti-inflammatory properties. In contrast with the irreversible action of manoalide (1) on phospholipase A2, luffariellolide (2) is a slightly less potent but partially reversible PLA2 inhibitor. © 1987 Birkhäuser Verlag.

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