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Is this really just “fatigue”? A case series of immune‐related central adrenal insufficiency secondary to immune checkpoint inhibitors

Creative Commons 'BY' version 4.0 license
Abstract

While immunotherapy with programmed cell death protein 1 (PD1) checkpoint inhibition has shown promising activity against many tumor types, adverse events are common. Hypophysitis is a rare but serious immune-related event known to occur with anti-PD1 inhibition. It will become more prevalent as the usage of checkpoint inhibitors increases.

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