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Elucidating the Mechanism of Action of Teixobactin
- Yang, Hyunjun
- Advisor(s): Nowick, James S
Abstract
This dissertation work is centered on understanding the structure and mechanism of action of the peptide antibiotic, teixobactin. Each chapter shares the themes of understanding the molecular recognition and supramolecular assembly of teixobactin. Each chapter shares the approach of chemical design, organic synthesis, and solution-/solid-phase study.