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Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells.

  • Author(s): Piomelli, D
  • Volterra, A
  • Dale, N
  • Siegelbaum, SA
  • Kandel, ER
  • Schwartz, JH
  • Belardetti, F
  • et al.

Published Web Location

https://doi.org/10.1038/328038a0Creative Commons 'BY' version 4.0 license
Abstract

Biochemical and biophysical studies on Aplysia sensory neurons indicate that inhibitory responses to the molluscan peptide FMRFamide are mediated by lipoxygenase metabolites of arachidonic acid. These compounds are a new class of second messengers in neurons.

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