Clinical Practice and Cases in Emergency Medicine
When Too Much Is Enough: Pediatric Cyproheptadine Overdose with Confirmatory Level
- Author(s): McGovern, Terrance
- McNamee, Justin
- Marcus, Steven
- Kashani, Josh
- et al.
Published Web Locationhttps://doi.org/10.5811/cpcem.2017.2.33313
Cyproheptadine is an H-1 antihistamine with anticholinergic and antiserotonergic effects.Cyproheptadine’s most common use has been in the management cold-induced urticaria. It is often usedin primary care for its side effect of appetite stimulation. Recently there has been increasing interest inits use in the treatment of drug-induced serotonin syndrome. Cyproheptadine overdose is uncommonlyreported in the medical literature. We report the rare case of a pediatric cyproheptadine overdose with aconfirmatory cyproheptadine level.