Skip to main content
eScholarship
Open Access Publications from the University of California

Hand-held high-throughput ultrasonic monodisperse aerosol inhalers for detoxification of massive cyanide poisoning

  • Author(s): Tsai, CS
  • Mao, RW
  • Zhu, Y
  • Chien, E
  • Maduzia, J
  • Tsai, SC
  • Brenner, M
  • Mahon, S
  • Mukai, D
  • Lee, J
  • Yoon, D
  • Berney, T
  • Boss, G
  • Patterson, S
  • et al.
Abstract

Detoxification of massive cyanide (CN) poisoning by inhalation of antidotes is recognized to be superior to intra venous (IV) or intra muscular (IM) treatment with regard to ease of administration, self-administration, and rapidity of onset. However, there are currently no effective, portable, high-throughput inhalers that can be produced in large quantities and distributed for such purpose. A hand-held inhaler has been realized using silicon-based ultrasonic nozzle to produce high-throughput of monodisperse cobinamide antidote solution for detoxification of CN poisoning in a rabbit model. © 2012 IEEE.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Main Content
Current View