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Parasite-induced T H 1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

  • Author(s): Defranco, Anthony
  • Raetz, M
  • Hwang, SH
  • Wilhelm, CL
  • Kirkland, D
  • Benson, A
  • Sturge, CR
  • Mirpuri, J
  • Vaishnava, S
  • Hou, B
  • Defranco, AL
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3552073?pdf=render
No data is associated with this publication.
Abstract

Activation of Toll-like receptors (TLRs) by pathogens triggers cytokine production and T cell activation, immune defense mechanisms that are linked to immunopathology. Here we show that IFN-γ production by CD4 + T H 1 cells during mucosal responses to the

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