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Open Access Publications from the University of California

Alteplase Causing Cardiac Tamponade in the Setting of Recent Cardiac Pacemaker Placement

  • Author(s): Warf, Corey J.
  • Huecker, Martin R.
  • O’Brien, Daniel J.
  • Bertolotti, Don A.
  • et al.

A 56-year-old female presented to the emergency department with evolving cardiac tamponade after receiving alteplase for acute ischemic stroke. This is the first case report of cardiac tamponade from thrombolytics in the setting of recent pacemaker placement. Point-of-care ultra sound was usedto make the diagnosis quickly and expedite the patient to the operating room where a pericardial window was performed.

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