Going retro: ancient viral origins of cognition.
- Author(s): Campioni, Matthew R
- Finkbeiner, Steven
- et al.
Published Web Locationhttps://doi.org/10.1016/j.neuron.2015.04.008
In this issue of Neuron, Zhang et al. (2015) provide the first crystal structure of a domain Arc. These results confirm prior computational approaches that suggested Arc, a master regulator of vertebrate synaptic plasticity, was "domesticated" from Ty3/Gypsy retrotransposons.