Going retro: Ancient viral origins of cognition
- Author(s): Campioni, MR
- Finkbeiner, S
- et al.
Published Web Locationhttps://doi.org/10.1016/j.neuron.2015.04.008
© 2015 Elsevier Inc. In this issue of Neuron, Zhang etal. (2015) provide the first crystal structure of a domain Arc. These results confirm prior computational approaches that suggested Arc, a master regulator of vertebrate synaptic plasticity, was "domesticated" from Ty3/Gypsy retrotransposons.