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A Therapy for Liver Failure Found in the JNK Yard

Published Web Location

https://doi.org/10.1016/j.cell.2013.03.033
Abstract

In the liver, the hepatocyte mass is kept stable through a tight balance between hepatocyte death and proliferation that is frequently lost upon acute or chronic liver injury. Wuestefeld et al. (2013) now identify a potentially druggable target that enhances hepatocyte proliferation and promotes liver regeneration, thereby preventing liver failure.

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