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A synthetic luciferin improves bioluminescence imaging in live mice
- Evans, Melanie S;
- Chaurette, Joanna P;
- Adams, Spencer T;
- Reddy, Gadarla R;
- Paley, Miranda A;
- Aronin, Neil;
- Prescher, Jennifer A;
- Miller, Stephen C
Published Web Location
https://doi.org/10.1038/nmeth.2839Abstract
The synthetic firefly luciferase substrate CycLuc1 offers brighter bioluminescence and improved imaging in mouse models at lower doses than the standard D-luciferin.
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