Skip to main content
eScholarship
Open Access Publications from the University of California

Scholarly Works (12 results)

  • Article
  • Peer Reviewed
American Indian Culture and Research Journal , Volume 45, Issue 1 (2021)
How is colonialism connected to American relationships with extraterrestrial beings? This commentary analyzes contemporary and founding US mythologies as constant, calculated attempts for settlers to obtain indigeneity in this land stemming from a fear of the “unknown.” From Columbus’s arrival to the Boston Tea Party, from alien and UFO fervor to paranormal experiences, spiritualism, New Age, and American Wicca, American mythology endlessly recreates conspiracy theories to justify its insatiable desire for resource extraction. I examine the US American mythology of extraterrestrials from two directions: the Oglala Lakota perspective of spirits born through a constellation of stars, and the “American” perspective of extraterrestrials born out of settler futurities. Manifest Destiny goes so far as to take ownership over time and reconfigure it into a linear, one-way street that is a progression towards apocalypse. For American Indians and other peoples targeted by the United States government, conspiracy theories prove true. Those who are targeted, Native and otherwise, understand as the violence of American mythology pours across the continent—abduction and assimilation, or death. How can Indigenous nonhuman ontologies orient settler ethics for the future?
    Cover page: “What’s on the earth is in the stars; and what’s in the stars is on the earth”: Lakota Relationships with the Stars and American Relationships with the ApocalypseCreative Commons 'BY-NC' version 4.0 license
    • Thesis
    • Peer Reviewed
    UC Berkeley Electronic Theses and Dissertations (2011)

    This thesis describes work related to long-term climate stability, on Mars and exoplanets.

    Mars is the only planet known to record a major transition in planetary habitability. The evidence for surface temperatures near the melting point of water on Early Mars is difficult to explain, because theory predicts a faint young Sun. Seasonal snowmelt need not require high annual mean temperatures, but surface water ice tends to migrate away from the warmer regions of the planet where melting is energetically possible. In the first part of this thesis I use geological analysis, mesoscale models, and idealized surface energy balance models to examine two possible solutions to this problem.

    Impacts into icy targets, groundwater outbursts, and phreatic explosions are all expected to inject water vapor into the Mars atmosphere. I use mesoscale models to track the atmospheric response to these transient, localized vapor sources. Using idealized boundary conditions, I show that storms with updraft speeds >50 m/s and localized precipitation are expected near transient lakes >10^3 km^2 in size. Snow deposited in this way is out of equilibrium with orbital forcing, and correspondingly more likely to melt. Canyon paleolakes in the Valles Marineris are frequently associated with streams preserved on the plateaux just downwind of the canyons. Using geologically realistic boundary conditions, I study the atmospheric response to two short-lived paleolakes. In each case, the plateau streams are in the locations expected for localized precipitation.

    Liquid water availability favors lithification, so the Martian sedimentary rock record is a wet-pass filter. Orbital variability strongly affects liquid water availability, so considering only averaged orbital conditions is neither sufficient not appropriate. To find the likelihood of snow melting, I consider all possible orbital forcings using an idealized but self-consistent model of snowpack energy balance and the CO2 greenhouse effect. Seasonal snowmelt on Early Mars is possible under unusual orbital conditions provided that the snow is dust-contaminated. The predicted distribution of snowmelt can explain the distribution of sedimentary rocks on Mars, but only if Mars had a thin atmosphere when the sedimentary rocks formed. This framework is the first to link upcoming observations by the Mars Science Laboratory Curiosity rover at the lower Gale Crater mound to past global climate on Mars. The model makes predictions about the lower Gale Crater mound that can be tested using Curiosity rover data.

    Earth is the only example of long term climate stability that is available for study, so long term climate stability is difficult to understand. Extrasolar planets may ameliorate this problem of uniqueness. It is clear that rates of volcanic activity and of surface weathering are important in regulating long term climate. In the second part of this thesis, I model the rate of volcanism on massive Earth-like planets, and the surface weathering rate on planets in 1:1 spin:orbit resonance. ``Super-Earths'' in the range 1-10 Earth masses have been detected by radial velocity and transit methods. Using an idealized mantle thermal evolution model to drive mantle-melting models, I show that the rate of volcanism on massive Earth like planets is a weak function of planet mass. Planet mass can, however, affect tectonics by changing the mode of mantle convection. Earth's climate stability depends on a negative feedback involving the temperature-dependent rate of weathering and mean surface temperature. I use an idealized model to show that for intermediate surface pressures and for low-opacity atmospheres, nonlinearities in the surface energy balance can reverse the sign of this dependence on tidally-locked planets. This leads to climate instability.

    I conclude by discussing future observations and research aimed at understanding long-term climate stability.

      Cover page: I. Climate change on ancient Mars. II. Exoplanet geodynamics and climate.
      • Article
      • Peer Reviewed
      UC Berkeley Previously Published Works (2018)
      Mars' surface bears the imprint of valley networks formed billions of years ago. Whether these networks were formed by groundwater sapping, ice melt, or fluvial runoff has been debated for decades. These different scenarios have profoundly different implications for Mars' climatic history and thus for its habitability in the distant past. Recent studies on Earth revealed that valley networks in arid landscapes with more surface runoff branch at narrower angles, while in humid environments with more groundwater flow, branching angles are much wider. We find that valley networks on Mars generally tend to branch at narrow angles similar to those found in arid landscapes on Earth. This result supports the inference that Mars once had an active hydrologic cycle and that Mars' valley networks were formed primarily by overland flow erosion, with groundwater seepage playing only a minor role.
        Cover page: Branching geometry of valley networks on Mars and Earth and its implications for early Martian climate
        • Article
        • Peer Reviewed
        UC Irvine Previously Published Works (2021)
        BACKGROUND: Hand genes are required for the development of the vertebrate jaw, heart, peripheral nervous system, limb, gut, placenta, and decidua. Two Hand paralogues, Hand1 and Hand2, are present in most vertebrates, where they mediate different functions yet overlap in expression. In ray-finned fishes, Hand gene expression and function is only known for the zebrafish, which represents the rare condition of having a single Hand gene, hand2. Here we describe the developmental expression of hand1 and hand2 in the cichlid Copadichromis azureus. RESULTS: hand1 and hand2 are expressed in the cichlid heart, paired fins, pharyngeal arches, peripheral nervous system, gut, and lateral plate mesoderm with different degrees of overlap. CONCLUSIONS: Hand gene expression in the gut, peripheral nervous system, and pharyngeal arches may have already been fixed in the lobe- and ray-finned fish common ancestor. In other embryonic regions, such as paired appendages, hand2 expression was fixed, while hand1 expression diverged in lobe- and ray-finned fish lineages. In the lateral plate mesoderm and arch associated catecholaminergic cells, hand1 and hand2 swapped expression between divergent lineages. Distinct expression of cichlid hand1 and hand2 in the epicardium and myocardium of the developing heart may represent the ancestral pattern for bony fishes.
          Cover page: A show of Hands: Novel and conserved expression patterns of teleost hand paralogs during craniofacial, heart, fin, peripheral nervous system and gut development.
          • Article
          • Peer Reviewed
          UCLA Previously Published Works (2022)
          The spectroscopic characterization of terrestrial exoplanets over a wide spectral range from the near- to the mid-infrared will be made possible for the first time with the JWST. One challenge is that it is not known a priori whether such planets possess optically thick atmospheres or even any atmospheres altogether. However, this challenge also presents an opportunity, the potential to detect the surface of an extrasolar world. This study explores the feasibility of characterizing with the JWST the atmosphere and surface of LHS 3844b, the highest signal-to-noise rocky thermal emission target among planets that are cool enough to have nonmolten surfaces. We model the planetary emission, including the spectral signal of both the atmosphere and surface, and we explore all scenarios that are consistent with the existing Spitzer 4.5 μm measurement of LHS 3844b from Kreidberg et al. In summary, we find a range of plausible surfaces and atmospheres that are within 3σ of the observationless reflective metal-rich, iron-oxidized, and basaltic compositions are allowed, and atmospheres are restricted to a maximum thickness of 1 bar, if near-infrared absorbers at ≳100 ppm are included. We further make predictions on the observability of surfaces and atmospheres and find that a small number (∼3) of eclipse observations should suffice to differentiate between surface and atmospheric features. We also perform a Bayesian retrieval analysis on simulated JWST data and find that the surface signal may make it harder to precisely constrain the abundance of atmospheric species and may falsely induce a weak H2O detection.
            Cover page: The Detectability of Rocky Planet Surface and Atmosphere Composition with the JWST: The Case of LHS 3844bCreative Commons 'BY' version 4.0 license
            • Article
            • Peer Reviewed
            UCLA Previously Published Works (2015)
            Autism spectrum disorder (ASD) is a heritable, common neurodevelopmental disorder with diverse genetic causes. Several studies have implicated protein synthesis as one among several of its potential convergent mechanisms. We originally identified Janus kinase and microtubule-interacting protein 1 (JAKMIP1) as differentially expressed in patients with distinct syndromic forms of ASD, fragile X syndrome, and 15q duplication syndrome. Here, we provide multiple lines of evidence that JAKMIP1 is a component of polyribosomes and an RNP translational regulatory complex that includes fragile X mental retardation protein, DEAD box helicase 5, and the poly(A) binding protein cytoplasmic 1. JAKMIP1 loss dysregulates neuronal translation during synaptic development, affecting glutamatergic NMDAR signaling, and results in social deficits, stereotyped activity, abnormal postnatal vocalizations, and other autistic-like behaviors in the mouse. These findings define an important and novel role for JAKMIP1 in neural development and further highlight pathways regulating mRNA translation during synaptogenesis in the genesis of neurodevelopmental disorders.
              Cover page: JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse
              • Article
              • Peer Reviewed
              UC Riverside Previously Published Works (2022)
                Cover page: Exogeoscience and Its Role in Characterizing Exoplanet Habitability and the Detectability of Life
                • Article
                • Peer Reviewed
                UC Berkeley Previously Published Works (2016)
                What allows a planet to be both within a potentially habitable zone and sustain habitability over long geologic time? With the advent of exoplanetary astronomy and the ongoing discovery of terrestrial-type planets around other stars, our own solar system becomes a key testing ground for ideas about what factors control planetary evolution. Mars provides the solar system's longest record of the interplay of the physical and chemical processes relevant to habitability on an accessible rocky planet with an atmosphere and hydrosphere. Here we review current understanding and update the timeline of key processes in early Mars history. We then draw on knowledge of exoplanets and the other solar system terrestrial planets to identify six broad questions of high importance to the development and sustaining of habitability (unprioritized): (1) Is small planetary size fatal? (2) How do magnetic fields influence atmospheric evolution? (3) To what extent does starting composition dictate subsequent evolution, including redox processes and the availability of water and organics? (4) Does early impact bombardment have a net deleterious or beneficial influence? (5) How do planetary climates respond to stellar evolution, e.g., sustaining early liquid water in spite of a faint young Sun? (6) How important are the timescales of climate forcing and their dynamical drivers? Finally, we suggest crucial types of Mars measurements (unprioritized) to address these questions: (1) in situ petrology at multiple units/sites; (2) continued quantification of volatile reservoirs and new isotopic measurements of H, C, N, O, S, Cl, and noble gases in rocks that sample multiple stratigraphic sections; (3) radiometric age dating of units in stratigraphic sections and from key volcanic and impact units; (4) higher-resolution measurements of heat flux, subsurface structure, and magnetic field anomalies coupled with absolute age dating. Understanding the evolution of early Mars will feed forward to understanding the factors driving the divergent evolutionary paths of the Earth, Venus, and thousands of small rocky extrasolar planets yet to be discovered.
                  • Article
                  • Peer Reviewed
                  UC San Francisco Previously Published Works (2024)
                  Meningiomas are the most common primary intracranial tumors and can be associated with significant morbidity and mortality. Radiologists, neurosurgeons, neuro-oncologists, and radiation oncologists rely on brain MRI for diagnosis, treatment planning, and longitudinal treatment monitoring. However, automated, objective, and quantitative tools for non-invasive assessment of meningiomas on multi-sequence MR images are not available. Here we present the BraTS Pre-operative Meningioma Dataset, as the largest multi-institutional expert annotated multilabel meningioma multi-sequence MR image dataset to date. This dataset includes 1,141 multi-sequence MR images from six sites, each with four structural MRI sequences (T2-, T2/FLAIR-, pre-contrast T1-, and post-contrast T1-weighted) accompanied by expert manually refined segmentations of three distinct meningioma sub-compartments: enhancing tumor, non-enhancing tumor, and surrounding non-enhancing T2/FLAIR hyperintensity. Basic demographic data are provided including age at time of initial imaging, sex, and CNS WHO grade. The goal of releasing this dataset is to facilitate the development of automated computational methods for meningioma segmentation and expedite their incorporation into clinical practice, ultimately targeting improvement in the care of meningioma patients.
                    Cover page: A multi-institutional meningioma MRI dataset for automated multi-sequence image segmentation.
                    • Article
                    • Peer Reviewed
                    UC San Diego Previously Published Works (2024)
                      Creative Commons 'BY' version 4.0 license
                      Top