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Open Access Publications from the University of California

High nasal burden of methicillin-resistant staphylococcus aureus increases risk of invasive disease

  • Author(s): Datta, R
  • Shah, A
  • Huang, SS
  • Cui, E
  • Nguyen, V
  • Welbourne, SJ
  • Quan, KA
  • Thrupp, L
  • et al.

In a retrospective cohort study of 1,140 patients harboring methicillin-resistant Staphylococcus aureus, the nasal burden was low in 31%, category 1to 2in 54%, and category 3to 4in 15%. There was a significant trend in infection risk with increasing nasal burden (P0.007). In multivariate models, high nasal burden remained significantly associated with invasive infection. Copyright © 2014, American Society for Microbiology.

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