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Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation.
- Adler, Frederick;
- Anderson, Alexander;
- Bhushan, Abhinav;
- Bogdan, Paul;
- Bravo-Cordero, Jose;
- Brock, Amy;
- Chen, Yun;
- Cukierman, Edna;
- DelGiorno, Kathleen;
- Denis, Gerald;
- Ferrall-Fairbanks, Meghan;
- Gartner, Zev;
- Germain, Ronald;
- Gordon, Deborah;
- Hunter, Ginger;
- Jolly, Mohit;
- Karacosta, Loukia;
- Mythreye, Karthikeyan;
- Katira, Parag;
- Kulkarni, Rajan;
- Kutys, Matthew;
- Lander, Arthur;
- Laughney, Ashley;
- Levine, Herbert;
- Lou, Emil;
- Lowenstein, Pedro;
- Masters, Kristyn;
- Peer, Dana;
- Peyton, Shelly;
- Platt, Manu;
- Purvis, Jeremy;
- Quon, Gerald;
- Richer, Jennifer;
- Riddle, Nicole;
- Rodriguez, Analiz;
- Snyder, Joshua;
- Lee Szeto, Gregory;
- Tomlin, Claire;
- Yanai, Itai;
- Zervantonakis, Ioannis;
- Dueck, Hannah
- et al.
Published Web Location
https://doi.org/10.1016/j.cels.2023.03.002Abstract
Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.
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