Skip to main content
eScholarship
Open Access Publications from the University of California

Association of self-reported and objective measures of physical exercise with leg muscle mitochondrial oxidative capacity in CKD

Abstract

Chronic kidney disease (CKD) is associated with skeletal muscle dysfunction leading to decreased physical functioning. Reduced kidney function leads to impaired muscle mitochondrial oxidative capacity underlying poor physical performance. The link between muscle mitochondrial oxidative capacity and patient-reported vs. objective measures of physical activity (PA) remains unclear. Objective: Determine the association between in-vivo leg muscle mitochondrial capacity and self-reported PA and objective PA.