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Bridging the synthetic and biopolymer worlds with peptide-drug conjugates.
- Author(s): Weiss, Gregory A
- Chamberlin, Richard
- et al.
Published Web Locationhttps://doi.org/10.1016/s1074-5521(03)00056-5
Roberts and Li break the standard library mold by generating hybrid libraries of small molecules tethered to peptides. Hybrid libraries harness larger chemical and structural diversities and thus represent a new frontier in lead drug discovery.