Lawrence Berkeley National Laboratory
Review of Bioassays for Monitoring Fate and Transport of Estrogenic Endocrine Disrupting
Compounds in Water
- Author(s): Campbell, Chris G.
- Borglin, Sharon E.
- Stringfellow, William T.
- Green, F. Bailey
- Grayson, Allen
- et al.
Endocrine disrupting compounds (EDCs) are recognized contaminants threatening water quality. Despite efforts in source identification, few strategies exist for characterization or treatment of this environmental pollution. Given that there are numerous EDCs that can negatively affect humans and wildlife, general screening techniques like bioassays and biosensors provide an essential rapid and intensive analysis capacity. Commonly applied bioassays include the ELISA and YES assays, but promising technologies include ER-CALUXa, ELRA, Endotecta, RIANA, and IR-bioamplification. Two biosensors, Endotecta and RIANA, are field portable using non-cellular biological detection strategies. Environmental management of EDCs in water requires integration of biosensors and bioassays for monitoring and assessment.