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Pragmatic trials with prespecified subgroups: what oncologists can learn from COVID-19

Published Web Location

https://doi.org/10.1038/s41571-020-00448-y
Creative Commons 'BY' version 4.0 license
Abstract

Randomized controlled trials designed to test cancer therapies often fail to clarify effectiveness in real-world settings. Herein, we explore lessons for trial development in oncology that can be learnt from the large-cohort, pragmatic RECOVERY trial involving patients hospitalized with COVID-19.

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