The Journal of Citrus Pathology in an international, peer-reviewed, open access, online publication. The Journal of Citrus Pathology welcomes reports on research from all branches of pathology on all diseases of citrus and related fields. The journal accepts original contributions in basic and applied research on citrus diseases, pathogens and disease-associated agents, including graft-transmissible agents, viruses, viroids, bacteria, phytoplasmas and other wall-less bacteria, fungi, oomycetes, and nematodes as well as any agents affecting citrus biology. This on-line IOCV publication by eScholarship ensures the distribution of critical information for citrus health and hosts occasional invited autobiographies and biographies of pioneer leaders of the field of citrus pathology.
Volume 6, Issue 1, 2019
The physical effects of disease induced by Citrus tristeza virus (CTV) on its citrus host have long been known, but not how disease is induced either by the virus, or its effects on the host at the genetic level. In this study we aimed to examine the latter, by deliberate inoculation of Citrus macrophylla with a mutant T36-based infectious clone known to induce stem pitting and other growth abnormalities. The microRNA populations of disease-expressing plants were compared with plants infected with asymptomatic, wild-type T36, and with un-inoculated controls. We found that while virus infection induced change in expression of a large number of miRNAs, the onset of disease correlated with the downregulation of miR164, a miRNA associated with vascular differentiation. This is the first evidence of specific host miRNAs associated with the induction of a CTV disease syndrome.
Biography of Stephen M Garnsey