Mediterranean Journal of Emergency Medicine & Acute Care

Loxosceles genus represents a wide number of species including the brown recluse spider. This spider is known worldwide for causing serious injuries resulting from its bite. The diagnosis of brown recluse spider bite is challenging as the injury clinically resembles other conditions and cannot be confirmed unless the spider was observed. We present a case of a 46-year-old male who presented to the emergency department with sudden onset of two painful punctate lesions. We discuss the clinical presentation, investigation and approach; additionally, we briefly highlight the main points with regards to presentation, diagnosis and management of this condition.