UC Santa Cruz
The Mouse Superior Colliculus: An Emerging Model for Studying Circuit Formation and Function.
- Author(s): Ito, Shinya
- Feldheim, David A
- et al.
Published Web Locationhttps://doi.org/10.3389/fncir.2018.00010
The superior colliculus (SC) is a midbrain area where visual, auditory and somatosensory information are integrated to initiate motor commands. The SC plays a central role in visual information processing in the mouse; it receives projections from 85% to 90% of the retinal ganglion cells (RGCs). While the mouse SC has been a long-standing model used to study retinotopic map formation, a number of technological advances in mouse molecular genetic techniques, large-scale physiological recordings and SC-dependent visual behavioral assays have made the mouse an even more ideal model to understand the relationship between circuitry and behavior.