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Resting State Functional Connectivity in Children: A New Paradigm

Abstract

Resting state functional connectivity (rsFC) can provide awindow into the neural architecture of functional networks inthe brain. Functional networks measured both during task andduring “resting” (task-absent) state are correlated withcognitive function, and much development of these networksoccurs between infancy and adulthood. However, rsFC studyin young children has been sparse, mainly due to a paucity ofchild-appropriate neural measures and behavioral paradigms.We present a new paradigm to measure rsFC in children,utilizing functional near-infrared spectroscopy (fNIRS) andFreeplay, a behavioral setup designed to approximate restingstate in children. Results suggest this paradigm is practicaland has good construct validity and test-retest reliability.

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