UCLA Radiological Sciences Proceedings

Zinner syndrome is a rare congenital anomaly resulting from mesonephric duct maldevelopment and characterized by the triad of ipsilateral renal agenesis, seminal vesicle cyst(s), and ejaculatory duct obstruction. We report the unique case of an 18-year-old man with a history of solitary right kidney and prior left varicocele ligation, who presented with left scrotal pain and swelling. This case represents a rare presentation of Zinner syndrome with both multiloculated and hemorrhagic seminal vesicle cysts. It underscores the importance of multimodal imaging and histopathological evaluation in diagnosing atypical variants of Zinner syndrome and guiding surgical intervention.