Volume 6, Issue 3, 2026
Case Reports
- Malignant Phyllodes Tumor of the Breast: A Case Report
Malignant phyllodes tumors are rare fibroepithelial neoplasms, comprising less than 1% of all breast tumors. We report the case of a 46-year-old woman who presented with a rapidly enlarging right breast mass. Serial imaging revealed progressive growth from 1.1 cm to over 7 cm. Initial core biopsies suggested an atypical lipomatous neoplasm or well-differentiated liposarcoma. Features of phyllodes tumor were not seen. Multidisciplinary review recommended surgical excision. The patient underwent a skin-sparing mastectomy with wide margins. Final pathology confirmed a 7.1 cm malignant phyllodes tumor with high-grade liposarcoma. Postoperative management included post-mastectomy radiation due to close posterior margins. This case underscores the diagnostic challenges of lipomatous lesions occurring in phyllodes tumors, highlights the importance of clinicopathologic correlation, and demonstrates the critical role of multidisciplinary evaluation in managing rare and diagnostically challenging breast tumors.
- Zinner Syndrome: A Case Report
Zinner syndrome is a rare congenital anomaly resulting from mesonephric duct maldevelopment and characterized by the triad of ipsilateral renal agenesis, seminal vesicle cyst(s), and ejaculatory duct obstruction. We report the unique case of an 18-year-old man with a history of solitary right kidney and prior left varicocele ligation, who presented with left scrotal pain and swelling. This case represents a rare presentation of Zinner syndrome with both multiloculated and hemorrhagic seminal vesicle cysts. It underscores the importance of multimodal imaging and histopathological evaluation in diagnosing atypical variants of Zinner syndrome and guiding surgical intervention.
- Pediatric Calcifying Nested Stromal-Epithelial Tumor of the Liver: A Case Report
Calcifying nested stromal-epithelial tumor (CNSET) of the liver is a rare primary hepatic neoplasm that classically presents as a solid mass with calcifications and predominantly affects children and young adults. It is typically a solitary liver mass that either is discovered incidentally on imaging or presents with abdominal symptoms, such as distension. We describe the case of a 14-year-old girl who presented with abdominal distention associated with a sensation of abdominal rigidity and back swelling. Repeated imaging and histologic examination revealed CNSET of the liver. This report provides new details regarding the imaging spectrum of this entity and highlights key diagnostic considerations in the assessment of CNSET.