UCLA Radiological Sciences Proceedings

Cherubism is a rare genetic disorder resulting in the replacement of the mandible and sometimes the maxilla with expansile cystic lesions. The disorder usually presents in childhood, with eventual quiescence in early adulthood. We report a case of cherubism involving both the mandible and the maxilla and complicated by mass effect on the nasal cavity and the left orbit. Pathologic features, clinical considerations, and treatment of cherubism are discussed.