UCLA Radiological Sciences Proceedings

Breast metastasis from gastric adenocarcinoma is exceptionally rare, with only a small number of cases reported in the literature. These metastases often occur in premenopausal women and commonly involve the signet ring cell subtype, usually presenting as unilateral, left breast lesions. We present the case of a 33-year-old Asian woman with signet ring cell gastric adenocarcinoma who developed bilateral breast metastases. This case illustrates the diagnostic challenges associated with this rare metastasis and highlights the essential role of multimodal imaging and biopsy in confirming the diagnosis. Early recognition of the condition is critical given the poor prognosis and lack of standardized treatment.